Who shouldn’t use these medications: Individuals with allergy to gemcitabine shouldn’t take it. Routine: Antimetabolites are given as an IV injection each week for the first 3 weeks of each 4-week chemotherapy cycle. Drug or meals interactions: Antimetabolites may raise the effects of warfarin . Unwanted effects: Antimetabolites may cause a person to bleed or to develop infections more easily. A health care provider will check urine and bloodstream for abnormalities which may be due to these drugs. A doctor ought to be contacted immediately if any of the following side effects occur: Unexplained fever, chills, or sore throat Serious nausea, vomiting, or diarrhea Unusual bleeding or bruising Small reddish or purple dots on the skin Yellowing of pores and skin or eye Wheezing or problems breathing Serious rash or hives Bloody or cloudy urine Other side effects are the following: Poor appetite Diarrhea or constipation Muscles pain Hair loss Mild rash Numbness, tingling, or mild swelling in the hands or feet Tiredness.... Breast cancer patients not really obtaining recommended radiation therapy: Report By Dr Ananya Mandal, MD According to a written report released Monday in the journal Tumor, nearly half of older ladies with advanced stage breasts cancer who go through a mastectomy don’t receive radiation therapy, despite guidelines that say it can save lives. Because of their report the researchers from MD Anderson Tumor Center in Houston looked at data for a lot more than 38,000 women age group 66 and older who underwent a mastectomy after a breast cancer diagnosis between 1999 and 2005. Nearly 8,000 of whom had a sophisticated form of the condition. They write that although major guidelines released through the six-year period suggested radiation therapy after mastectomy for females with advanced forms of the disease, nearly fifty % of the ladies whose records the researchers analyzed throughout that period did not receive the therapy.